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Saturday 01 January 2000

Complete response to topotecan of recurrent fallopian tube carcinoma.

By: Dunton CJ, Neufeld J.

Gynecol Oncol 2000 Jan;76(1):128-9

OBJECTIVE: To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan. METHODS: A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described. RESULTS: This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments. CONCLUSION: Topotecan appears active in recurrent Fallopian tube carcinoma. Copyright 2000 Academic Press.

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